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The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation

BACKGROUND: Limited studies examine the immune landscape in Esophageal Adenocarcinoma (EAC). We aim to identify novel associations, which may inform immunotherapy treatment stratification. METHODS: Three hundred twenty-nine EAC cases were available in Tissue Microarrays (TMA) format. A discovery coh...

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Detalles Bibliográficos
Autores principales:	Humphries, Matthew P., Craig, Stephanie G., Kacprzyk, Rafal, Fisher, Natalie C., Bingham, Victoria, McQuaid, Stephen, Murray, Graeme I., McManus, Damian, Turkington, Richard C., James, Jacqueline, Salto-Tellez, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268770/ https://www.ncbi.nlm.nih.gov/pubmed/32487090 http://dx.doi.org/10.1186/s12885-020-06987-y

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