Advances in blood–brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure

BACKGROUND: The United States faces a national crisis involving opioid medications, where currently more than 130 people die every day. To combat this epidemic, a better understanding is needed of how opioids penetrate into the central nervous system (CNS) to facilitate pain relief and, potentially,...

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Detalles Bibliográficos
Autores principales: Brown, Jacquelyn A., Faley, Shannon L., Shi, Yajuan, Hillgren, Kathleen M., Sawada, Geri A., Baker, Thomas K., Wikswo, John P., Lippmann, Ethan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269003/
https://www.ncbi.nlm.nih.gov/pubmed/32493346
http://dx.doi.org/10.1186/s12987-020-00200-9

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