Chiral 4-O-acylterpineol as transdermal permeation enhancers: insights of the enhancement mechanisms of a transdermal enantioselective delivery system for flurbiprofen

In order to devise more effective penetration enhancers, 4-O-acylterpineol derivatives which were expected to be hydrolyzed into nontoxic metabolites by esterase in the living epidermis, were synthesized from 4-terpineol (4-TER) enantiomers and straight chain fatty acids. Their promoting activities...

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Detalles Bibliográficos
Autores principales: Chu, Tianzhe, Wang, Chunyan, Wang, Jing, Wang, Heping, Geng, Dandan, Wu, Chensi, Zhao, Linlin, Zhao, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269032/
https://www.ncbi.nlm.nih.gov/pubmed/32397753
http://dx.doi.org/10.1080/10717544.2020.1760403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269032/
https://www.ncbi.nlm.nih.gov/pubmed/32397753
http://dx.doi.org/10.1080/10717544.2020.1760403

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