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Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles

It is reported that quercetin (Que) can prevent tau pathology and induce neuroprotection by improving cognitive and functional symptoms in the treatment of Alzheimer’s disease (AD). However, its clinical application has been limited due to its poor brain targeting and bioavailability. Exosomes are c...

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Detalles Bibliográficos
Autores principales:	Qi, Yao, Guo, Lin, Jiang, Yibing, Shi, Yijie, Sui, Haijuan, Zhao, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269046/ https://www.ncbi.nlm.nih.gov/pubmed/32397764 http://dx.doi.org/10.1080/10717544.2020.1762262

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