Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma

Targeted inhibition of proteins modulating epigenetic changes is an increasingly important priority in cancer therapeutics, and many small molecule inhibitors are currently being developed. In the case of neuroblastoma (NB), a pediatric solid tumor with a paucity of intragenic mutations, epigenetic...

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Detalles Bibliográficos
Autores principales: Bellamy, Jacob, Szemes, Marianna, Melegh, Zsombor, Dallosso, Anthony, Kollareddy, Madhu, Catchpoole, Daniel, Malik, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269128/
https://www.ncbi.nlm.nih.gov/pubmed/32537432
http://dx.doi.org/10.3389/fonc.2020.00818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269128/
https://www.ncbi.nlm.nih.gov/pubmed/32537432
http://dx.doi.org/10.3389/fonc.2020.00818

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