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DeconPeaker, a Deconvolution Model to Identify Cell Types Based on Chromatin Accessibility in ATAC-Seq Data of Mixture Samples

While our understanding of cellular and molecular processes has grown exponentially, issues related to the cell microenvironment and cellular heterogeneity have sparked a new debate concerning the cell identity. Cell composition (chromatin and nuclear architecture) poses a strong risk for dynamic ch...

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Detalles Bibliográficos
Autores principales: Li, Huamei, Sharma, Amit, Luo, Kun, Qin, Zhaohui S., Sun, Xiao, Liu, Hongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269180/
https://www.ncbi.nlm.nih.gov/pubmed/32547592
http://dx.doi.org/10.3389/fgene.2020.00392