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Strawberry gingivitis – First sign of Wegener's granulomatosis

Wegener's Granulomatosis (WG) is an immunologically mediated rare multisystem disease characterized by necrotizing granulomatous inflammation affecting the upper and lower respiratory tracts, disseminated vasculitis and glomerulonephritis. WG oral lesions are reported to occur in 6%–13% of pati...

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Autores principales: Dhalkari, Chandulal D., Patil, Sayali Chandrakant, Indurkar, Maya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269271/
https://www.ncbi.nlm.nih.gov/pubmed/32508469
http://dx.doi.org/10.4103/jomfp.JOMFP_3_19
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author Dhalkari, Chandulal D.
Patil, Sayali Chandrakant
Indurkar, Maya S.
author_facet Dhalkari, Chandulal D.
Patil, Sayali Chandrakant
Indurkar, Maya S.
author_sort Dhalkari, Chandulal D.
collection PubMed
description Wegener's Granulomatosis (WG) is an immunologically mediated rare multisystem disease characterized by necrotizing granulomatous inflammation affecting the upper and lower respiratory tracts, disseminated vasculitis and glomerulonephritis. WG oral lesions are reported to occur in 6%–13% of patients; they were an initial presenting feature in only 2% of cases. A case of strawberry gingivitis as the first sign of WG presented with erythematous and painful localized gingival enlargement affecting the maxillary anterior region of jaw in a 17-year-old boy is reported here. Correlation of histopathology with routine hematoxylin and eosin and special stains such as Grocott-Gomori's methenamine-silver nitrate and periodic acid–Schiff, peripheral blood smear, chest radiographs, Mantoux test and clinical presentation were established in diagnosing this rare entity. By the above-mentioned procedures, we arrived at the diagnosis of WG. The aim of reporting this case was to emphasize that, the dental surgeon often being the first person to examine the oral cavity, should be familiar with the typical appearance of gingiva as “strawberry gingivitis,” its clinical course, diagnostic parameters and adequate management of WG.
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spelling pubmed-72692712020-06-05 Strawberry gingivitis – First sign of Wegener's granulomatosis Dhalkari, Chandulal D. Patil, Sayali Chandrakant Indurkar, Maya S. J Oral Maxillofac Pathol Case Report Wegener's Granulomatosis (WG) is an immunologically mediated rare multisystem disease characterized by necrotizing granulomatous inflammation affecting the upper and lower respiratory tracts, disseminated vasculitis and glomerulonephritis. WG oral lesions are reported to occur in 6%–13% of patients; they were an initial presenting feature in only 2% of cases. A case of strawberry gingivitis as the first sign of WG presented with erythematous and painful localized gingival enlargement affecting the maxillary anterior region of jaw in a 17-year-old boy is reported here. Correlation of histopathology with routine hematoxylin and eosin and special stains such as Grocott-Gomori's methenamine-silver nitrate and periodic acid–Schiff, peripheral blood smear, chest radiographs, Mantoux test and clinical presentation were established in diagnosing this rare entity. By the above-mentioned procedures, we arrived at the diagnosis of WG. The aim of reporting this case was to emphasize that, the dental surgeon often being the first person to examine the oral cavity, should be familiar with the typical appearance of gingiva as “strawberry gingivitis,” its clinical course, diagnostic parameters and adequate management of WG. Wolters Kluwer - Medknow 2020 2020-05-08 /pmc/articles/PMC7269271/ /pubmed/32508469 http://dx.doi.org/10.4103/jomfp.JOMFP_3_19 Text en Copyright: © 2020 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Dhalkari, Chandulal D.
Patil, Sayali Chandrakant
Indurkar, Maya S.
Strawberry gingivitis – First sign of Wegener's granulomatosis
title Strawberry gingivitis – First sign of Wegener's granulomatosis
title_full Strawberry gingivitis – First sign of Wegener's granulomatosis
title_fullStr Strawberry gingivitis – First sign of Wegener's granulomatosis
title_full_unstemmed Strawberry gingivitis – First sign of Wegener's granulomatosis
title_short Strawberry gingivitis – First sign of Wegener's granulomatosis
title_sort strawberry gingivitis – first sign of wegener's granulomatosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269271/
https://www.ncbi.nlm.nih.gov/pubmed/32508469
http://dx.doi.org/10.4103/jomfp.JOMFP_3_19
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