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Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study

BACKGROUND: Despite our sincere and serious efforts, oral cancer (particularly oral squamous cell carcinoma [OSCC]) is the major cause of morbidity and mortality in the Indian population. Oral precancerous lesions show quite high malignant transformation rate. Epidemiological data of oral epithelial...

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Autores principales: Singh, Shruti, Singh, Jaya, Chandra, Shaleen, Samadi, Fahad Mansoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269288/
https://www.ncbi.nlm.nih.gov/pubmed/32508454
http://dx.doi.org/10.4103/jomfp.JOMFP_347_19
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author Singh, Shruti
Singh, Jaya
Chandra, Shaleen
Samadi, Fahad Mansoor
author_facet Singh, Shruti
Singh, Jaya
Chandra, Shaleen
Samadi, Fahad Mansoor
author_sort Singh, Shruti
collection PubMed
description BACKGROUND: Despite our sincere and serious efforts, oral cancer (particularly oral squamous cell carcinoma [OSCC]) is the major cause of morbidity and mortality in the Indian population. Oral precancerous lesions show quite high malignant transformation rate. Epidemiological data of oral epithelial dysplasia (OED) and OSCC could help in early diagnosis and thus may improve the prognosis. The current study aims to retrospectively analyze the epidemiological profile of patients with different grades of OED and OSCCs. MATERIALS AND METHODS: The current study is a retrospective analysis of OED and OSCC reported in 5 years in our institution from 2014 to 2018. Data for the analysis were attained from the case sheets from the patients diagnosed with OED and OSCC. RESULTS: The mean prevalence of OED and OSCC was 5.71% and 9.85%, respectively. Among the dysplastic lesions, severe dysplasia was more common, while well-differentiated squamous cell carcinoma was more common among the carcinomatous lesions. The peak age prevalence of both the lesions was third to fifth decade. Males were more frequently affected than females, with buccal mucosa being the most common site. CONCLUSION: The data attained from this study highlight the need for community-based screening and awareness programs for general population and thus obtain a healthier society.
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spelling pubmed-72692882020-06-05 Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study Singh, Shruti Singh, Jaya Chandra, Shaleen Samadi, Fahad Mansoor J Oral Maxillofac Pathol Original Article BACKGROUND: Despite our sincere and serious efforts, oral cancer (particularly oral squamous cell carcinoma [OSCC]) is the major cause of morbidity and mortality in the Indian population. Oral precancerous lesions show quite high malignant transformation rate. Epidemiological data of oral epithelial dysplasia (OED) and OSCC could help in early diagnosis and thus may improve the prognosis. The current study aims to retrospectively analyze the epidemiological profile of patients with different grades of OED and OSCCs. MATERIALS AND METHODS: The current study is a retrospective analysis of OED and OSCC reported in 5 years in our institution from 2014 to 2018. Data for the analysis were attained from the case sheets from the patients diagnosed with OED and OSCC. RESULTS: The mean prevalence of OED and OSCC was 5.71% and 9.85%, respectively. Among the dysplastic lesions, severe dysplasia was more common, while well-differentiated squamous cell carcinoma was more common among the carcinomatous lesions. The peak age prevalence of both the lesions was third to fifth decade. Males were more frequently affected than females, with buccal mucosa being the most common site. CONCLUSION: The data attained from this study highlight the need for community-based screening and awareness programs for general population and thus obtain a healthier society. Wolters Kluwer - Medknow 2020 2020-05-08 /pmc/articles/PMC7269288/ /pubmed/32508454 http://dx.doi.org/10.4103/jomfp.JOMFP_347_19 Text en Copyright: © 2020 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Singh, Shruti
Singh, Jaya
Chandra, Shaleen
Samadi, Fahad Mansoor
Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
title Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
title_full Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
title_fullStr Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
title_full_unstemmed Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
title_short Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
title_sort prevalence of oral cancer and oral epithelial dysplasia among north indian population: a retrospective institutional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269288/
https://www.ncbi.nlm.nih.gov/pubmed/32508454
http://dx.doi.org/10.4103/jomfp.JOMFP_347_19
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