Cargando…

MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication

The quinoline MK-571 is the most commonly used inhibitor of multidrug resistance protein-1 (MRP-1) but was originally developed as a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist. While studying the modulatory effect of MRP-1 on anti-hepatitis C virus (HCV) direct-acting antiviral (DAA) effi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz, Isaac, Nevers, Quentin, Hernández, Eva, Ahnou, Nazim, Brillet, Rozenn, Softic, Laurent, Donati, Flora, Berry, Francois, Hamadat, Sabah, Fourati, Slim, Pawlotsky, Jean-Michel, Ahmed-Belkacem, Abdelhakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269486/
https://www.ncbi.nlm.nih.gov/pubmed/32179525
http://dx.doi.org/10.1128/AAC.02078-19