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MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication
The quinoline MK-571 is the most commonly used inhibitor of multidrug resistance protein-1 (MRP-1) but was originally developed as a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist. While studying the modulatory effect of MRP-1 on anti-hepatitis C virus (HCV) direct-acting antiviral (DAA) effi...
Autores principales: | Ruiz, Isaac, Nevers, Quentin, Hernández, Eva, Ahnou, Nazim, Brillet, Rozenn, Softic, Laurent, Donati, Flora, Berry, Francois, Hamadat, Sabah, Fourati, Slim, Pawlotsky, Jean-Michel, Ahmed-Belkacem, Abdelhakim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269486/ https://www.ncbi.nlm.nih.gov/pubmed/32179525 http://dx.doi.org/10.1128/AAC.02078-19 |
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