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Case series of sporotrichosis at a teaching hospital in Brazil

INTRODUCTION: Sporotrichosis is a subcutaneous fungal infection with a worldwide distribution and higher incidence in tropical and subtropical areas, such as the Brazilian territory, where it has been standing out due to its frequent epidemics. Thus, the present study aimed to evaluate the prevalenc...

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Autores principales: Benvegnú, Ana Maria, Dallazzem, Lia Natália Diehl, Chemello, Raíssa Massaia Londero, Beber, André Avelino Costa, Chemello, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269531/
https://www.ncbi.nlm.nih.gov/pubmed/32428177
http://dx.doi.org/10.1590/0037-8682-0509-2019
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author Benvegnú, Ana Maria
Dallazzem, Lia Natália Diehl
Chemello, Raíssa Massaia Londero
Beber, André Avelino Costa
Chemello, Diego
author_facet Benvegnú, Ana Maria
Dallazzem, Lia Natália Diehl
Chemello, Raíssa Massaia Londero
Beber, André Avelino Costa
Chemello, Diego
author_sort Benvegnú, Ana Maria
collection PubMed
description INTRODUCTION: Sporotrichosis is a subcutaneous fungal infection with a worldwide distribution and higher incidence in tropical and subtropical areas, such as the Brazilian territory, where it has been standing out due to its frequent epidemics. Thus, the present study aimed to evaluate the prevalence of sporotrichosis and profile the affected patients at a university teaching hospital in the central region of Rio Grande do Sul, Brazil. METHODS: This study was a case series of patients diagnosed with Sporothrix spp. from January 2006 to December 2015 by microscopic examination or fungal isolates. Medical records were reviewed for epidemiological data. RESULTS: Forty-three cases of sporotrichosis were diagnosed through the period. The sample comprised predominantly young male adults and rural workers. The most common disease type was lymphocutaneous (51%), followed by fixed cutaneous form (32.5%). The predominant location was the upper limbs (70%), followed by the lower limbs (16%). A significant association was observed between the lymphocutaneous form and upper limb location and between the fixed cutaneous form and lower limb location (p = 0.019). Potassium iodine and itraconazole were the most common treatments. CONCLUSIONS: This study will help update the epidemiological situation of sporotrichosis in the central region of the state of Rio Grande do Sul, Brazil, over the last decade.
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spelling pubmed-72695312020-06-05 Case series of sporotrichosis at a teaching hospital in Brazil Benvegnú, Ana Maria Dallazzem, Lia Natália Diehl Chemello, Raíssa Massaia Londero Beber, André Avelino Costa Chemello, Diego Rev Soc Bras Med Trop Major Article INTRODUCTION: Sporotrichosis is a subcutaneous fungal infection with a worldwide distribution and higher incidence in tropical and subtropical areas, such as the Brazilian territory, where it has been standing out due to its frequent epidemics. Thus, the present study aimed to evaluate the prevalence of sporotrichosis and profile the affected patients at a university teaching hospital in the central region of Rio Grande do Sul, Brazil. METHODS: This study was a case series of patients diagnosed with Sporothrix spp. from January 2006 to December 2015 by microscopic examination or fungal isolates. Medical records were reviewed for epidemiological data. RESULTS: Forty-three cases of sporotrichosis were diagnosed through the period. The sample comprised predominantly young male adults and rural workers. The most common disease type was lymphocutaneous (51%), followed by fixed cutaneous form (32.5%). The predominant location was the upper limbs (70%), followed by the lower limbs (16%). A significant association was observed between the lymphocutaneous form and upper limb location and between the fixed cutaneous form and lower limb location (p = 0.019). Potassium iodine and itraconazole were the most common treatments. CONCLUSIONS: This study will help update the epidemiological situation of sporotrichosis in the central region of the state of Rio Grande do Sul, Brazil, over the last decade. Sociedade Brasileira de Medicina Tropical - SBMT 2020-05-18 /pmc/articles/PMC7269531/ /pubmed/32428177 http://dx.doi.org/10.1590/0037-8682-0509-2019 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Major Article
Benvegnú, Ana Maria
Dallazzem, Lia Natália Diehl
Chemello, Raíssa Massaia Londero
Beber, André Avelino Costa
Chemello, Diego
Case series of sporotrichosis at a teaching hospital in Brazil
title Case series of sporotrichosis at a teaching hospital in Brazil
title_full Case series of sporotrichosis at a teaching hospital in Brazil
title_fullStr Case series of sporotrichosis at a teaching hospital in Brazil
title_full_unstemmed Case series of sporotrichosis at a teaching hospital in Brazil
title_short Case series of sporotrichosis at a teaching hospital in Brazil
title_sort case series of sporotrichosis at a teaching hospital in brazil
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269531/
https://www.ncbi.nlm.nih.gov/pubmed/32428177
http://dx.doi.org/10.1590/0037-8682-0509-2019
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