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VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response

Virulence-associated protein B and C toxin-antitoxin (TA) systems are widespread in prokaryotes, but their precise role in physiology is poorly understood. We have functionally characterized the VapBC22 TA system from Mycobacterium tuberculosis. Transcriptome analysis revealed that overexpression of...

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Detalles Bibliográficos
Autores principales:	Agarwal, Sakshi, Sharma, Arun, Bouzeyen, Rania, Deep, Amar, Sharma, Harsh, Mangalaparthi, Kiran K., Datta, Keshava K., Kidwai, Saqib, Gowda, Harsha, Varadarajan, Raghavan, Sharma, Ravi Datta, Thakur, Krishan Gopal, Singh, Ramandeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269643/ https://www.ncbi.nlm.nih.gov/pubmed/32537511 http://dx.doi.org/10.1126/sciadv.aba6944

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