Cargando…

Tau pathology in early Alzheimer's disease is linked to selective disruptions in neurophysiological network dynamics

Understanding the role of Tau protein aggregation in the pathogenesis of Alzheimer's disease is critical for the development of new Tau-based therapeutic strategies to slow or prevent dementia. We tested the hypothesis that Tau pathology is associated with functional organization of widespread...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kocagoncu, Ece, Quinn, Andrew, Firouzian, Azadeh, Cooper, Elisa, Greve, Andrea, Gunn, Roger, Green, Gary, Woolrich, Mark W., Henson, Richard N., Lovestone, Simon, Rowe, James B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269692/ https://www.ncbi.nlm.nih.gov/pubmed/32280029 http://dx.doi.org/10.1016/j.neurobiolaging.2020.03.009

Ejemplares similares

Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease
por: Kocagoncu, Ece, et al.
Publicado: (2022)

Imaging Aβ and tau in early stage Alzheimer’s disease with [(18)F]AV45 and [(18)F]AV1451
por: Firouzian, Azadeh, et al.
Publicado: (2018)

PET Tau and Amyloid-β Burden in Mild Alzheimer’s Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers
por: Koychev, Ivan, et al.
Publicado: (2017)

New Therapeutics in Alzheimer’s Disease Longitudinal Cohort study (NTAD): study protocol
por: Lanskey, Juliette Helene, et al.
Publicado: (2022)

Neurophysiological signatures of Alzheimer’s disease and frontotemporal lobar degeneration: pathology versus phenotype
por: Sami, Saber, et al.
Publicado: (2018)

The neurophysiological effect of NMDA-R antagonism of frontotemporal lobar degeneration is conditional on individual GABA concentration
por: Perry, Alistair, et al.
Publicado: (2022)

The relationship between frequency content and representational dynamics in the decoding of neurophysiological data
por: Higgins, Cameron, et al.
Publicado: (2022)

Evidence and implications of abnormal predictive coding in dementia
por: Kocagoncu, Ece, et al.
Publicado: (2021)

Additive pre-diagnostic and diagnostic value of routine blood-based biomarkers in the detection of colorectal cancer in the UK Biobank cohort
por: Tanriver, Gizem, et al.
Publicado: (2023)

Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability
por: Ng, Bryan, et al.
Publicado: (2022)

Impact of Tau on Neurovascular Pathology in Alzheimer's Disease
por: Canepa, Elisa, et al.
Publicado: (2021)

Clinical Neurophysiology in Alzheimer's Disease
por: Ferreri, Florinda, et al.
Publicado: (2011)

Pathological and neurophysiological outcomes of seeding human-derived tau pathology in the APP-KI NL-G-F and NL-NL mouse models of Alzheimer’s Disease
por: Tok, S., et al.
Publicado: (2022)

NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology
por: Rojo, Ana I., et al.
Publicado: (2017)

Editorial: Neurophysiology in Alzheimer's Disease and Dementia
por: Moretti, Davide V.
Publicado: (2016)

Neurophysiological trajectories in Alzheimer’s disease progression
por: Kudo, Kiwamu, et al.
Publicado: (2023)

Neurophysiology
por: Carpenter, R. H. S. (Roger H. S.), 1945-
Publicado: (2003)

No evidence that ‘fast-mapping’ benefits novel learning in healthy Older adults
por: Greve, Andrea, et al.
Publicado: (2014)

Assumptions behind scoring source and item memory impact on conclusions about memory: A reply to Kellen and Singmann's comment (2017)
por: Cooper, Elisa, et al.
Publicado: (2017)

Investigating Fast Mapping Task Components: No Evidence for the Role of Semantic Referent nor Semantic Inference in Healthy Adults
por: Cooper, Elisa, et al.
Publicado: (2019)

Little evidence for Fast Mapping (FM) in adults: A review and discussion
por: Cooper, Elisa, et al.
Publicado: (2018)

Assumptions behind scoring source versus item memory: Effects of age, hippocampal lesions and mild memory problems
por: Cooper, Elisa, et al.
Publicado: (2017)

Response to commentaries on our review of Fast Mapping in adults
por: Cooper, Elisa, et al.
Publicado: (2019)

p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells
por: Hooper, Claudie, et al.
Publicado: (2007)

CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease
por: Barthélemy, Nicolas R., et al.
Publicado: (2023)

Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release
por: Glennon, Elizabeth B, et al.
Publicado: (2020)

Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer’s disease
por: Kitamura, Soichiro, et al.
Publicado: (2018)

In vivo coupling of tau pathology and cortical thinning in Alzheimer's disease
por: Mak, Elijah, et al.
Publicado: (2018)

Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH
por: Killick, R., et al.
Publicado: (2013)

Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L166P amyloid mouse model of Alzheimer’s disease
por: Tok, S., et al.
Publicado: (2022)

Knowledge Is Power: Prior Knowledge Aids Memory for Both Congruent and Incongruent Events, but in Different Ways
por: Greve, Andrea, et al.
Publicado: (2018)

Neurophysiological Markers of Alzheimer’s Disease: Quantitative EEG Approach
por: Smailovic, Una, et al.
Publicado: (2019)

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease
por: Hsieh, Yi-Chen, et al.
Publicado: (2019)

Structure and Pathology of Tau Protein in Alzheimer Disease
por: Kolarova, Michala, et al.
Publicado: (2012)

Microglia in Alzheimer’s Disease in the Context of Tau Pathology
por: Perea, Juan Ramón, et al.
Publicado: (2020)

Alzheimer's Disease: Tau Pathology and Dysfunction of Endocytosis
por: Ando, Kunie, et al.
Publicado: (2021)

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
por: Lasagna-Reeves, Cristian A., et al.
Publicado: (2012)

Phospho-Tau and Cognitive Decline in Alzheimer's Disease. Commentary: Tau in physiology and pathology
por: DeFelipe, Javier
Publicado: (2016)

Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain
por: DeVos, Sarah L., et al.
Publicado: (2018)

PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Disease
por: Luna-Viramontes, Nabil Itzi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8q6mp12ed0rp79vljtet80uejj