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PDGFB-expressing mesenchymal stem cells improve human hematopoietic stem cell engraftment in immunodeficient mice

The bone marrow (BM) niche regulates multiple hematopoietic stem cell (HSC) processes. Clinical treatment for hematological malignancies by HSC transplantation often requires preconditioning via total body irradiation, which severely and irreversibly impairs the BM niche and HSC regeneration. Novel...

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Detalles Bibliográficos
Autores principales:	Yin, Xiuxiu, Hu, Linping, Zhang, Yawen, Zhu, Caiying, Cheng, Hui, Xie, Xiaowei, Shi, Ming, Zhu, Ping, Zhao, Xueying, Chen, Wanqiu, Zhang, Lu, Arakaki, Cameron, Hao, Sha, Wang, Mei, Cao, Wenbin, Ma, Shihui, Zhang, Xiao-Bing, Cheng, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269905/ https://www.ncbi.nlm.nih.gov/pubmed/31804621 http://dx.doi.org/10.1038/s41409-019-0766-z

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