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Monoclonal antibody as a potential anti-COVID-19

Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the gene...

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Detalles Bibliográficos
Autores principales: Jahanshahlu, Leila, Rezaei, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269943/
https://www.ncbi.nlm.nih.gov/pubmed/32534226
http://dx.doi.org/10.1016/j.biopha.2020.110337
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author Jahanshahlu, Leila
Rezaei, Nima
author_facet Jahanshahlu, Leila
Rezaei, Nima
author_sort Jahanshahlu, Leila
collection PubMed
description Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the genetic and structural similarity of the virus to severe acute respiratory syndrome coronavirus (SARS-CoV) created the potential for understanding disease pathogenesis. Researchers have published reports of specific monoclonal antibodies against to COVID-19 (B38, H4, 47D11) and hope that this method is effective. As well as studies on patients who are plasma therapy, the patient's condition shows improvement. The evidence for these studies is very promising and demonstrates the potential of monoclonal antibody therapy as a therapeutic approach and prevention of covid-19 infection.
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spelling pubmed-72699432020-06-05 Monoclonal antibody as a potential anti-COVID-19 Jahanshahlu, Leila Rezaei, Nima Biomed Pharmacother Article Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the genetic and structural similarity of the virus to severe acute respiratory syndrome coronavirus (SARS-CoV) created the potential for understanding disease pathogenesis. Researchers have published reports of specific monoclonal antibodies against to COVID-19 (B38, H4, 47D11) and hope that this method is effective. As well as studies on patients who are plasma therapy, the patient's condition shows improvement. The evidence for these studies is very promising and demonstrates the potential of monoclonal antibody therapy as a therapeutic approach and prevention of covid-19 infection. The Authors. Published by Elsevier Masson SAS. 2020-09 2020-06-04 /pmc/articles/PMC7269943/ /pubmed/32534226 http://dx.doi.org/10.1016/j.biopha.2020.110337 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Jahanshahlu, Leila
Rezaei, Nima
Monoclonal antibody as a potential anti-COVID-19
title Monoclonal antibody as a potential anti-COVID-19
title_full Monoclonal antibody as a potential anti-COVID-19
title_fullStr Monoclonal antibody as a potential anti-COVID-19
title_full_unstemmed Monoclonal antibody as a potential anti-COVID-19
title_short Monoclonal antibody as a potential anti-COVID-19
title_sort monoclonal antibody as a potential anti-covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269943/
https://www.ncbi.nlm.nih.gov/pubmed/32534226
http://dx.doi.org/10.1016/j.biopha.2020.110337
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