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Monoclonal antibody as a potential anti-COVID-19
Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the gene...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Masson SAS.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269943/ https://www.ncbi.nlm.nih.gov/pubmed/32534226 http://dx.doi.org/10.1016/j.biopha.2020.110337 |
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author | Jahanshahlu, Leila Rezaei, Nima |
author_facet | Jahanshahlu, Leila Rezaei, Nima |
author_sort | Jahanshahlu, Leila |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the genetic and structural similarity of the virus to severe acute respiratory syndrome coronavirus (SARS-CoV) created the potential for understanding disease pathogenesis. Researchers have published reports of specific monoclonal antibodies against to COVID-19 (B38, H4, 47D11) and hope that this method is effective. As well as studies on patients who are plasma therapy, the patient's condition shows improvement. The evidence for these studies is very promising and demonstrates the potential of monoclonal antibody therapy as a therapeutic approach and prevention of covid-19 infection. |
format | Online Article Text |
id | pubmed-7269943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Authors. Published by Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72699432020-06-05 Monoclonal antibody as a potential anti-COVID-19 Jahanshahlu, Leila Rezaei, Nima Biomed Pharmacother Article Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the genetic and structural similarity of the virus to severe acute respiratory syndrome coronavirus (SARS-CoV) created the potential for understanding disease pathogenesis. Researchers have published reports of specific monoclonal antibodies against to COVID-19 (B38, H4, 47D11) and hope that this method is effective. As well as studies on patients who are plasma therapy, the patient's condition shows improvement. The evidence for these studies is very promising and demonstrates the potential of monoclonal antibody therapy as a therapeutic approach and prevention of covid-19 infection. The Authors. Published by Elsevier Masson SAS. 2020-09 2020-06-04 /pmc/articles/PMC7269943/ /pubmed/32534226 http://dx.doi.org/10.1016/j.biopha.2020.110337 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Jahanshahlu, Leila Rezaei, Nima Monoclonal antibody as a potential anti-COVID-19 |
title | Monoclonal antibody as a potential anti-COVID-19 |
title_full | Monoclonal antibody as a potential anti-COVID-19 |
title_fullStr | Monoclonal antibody as a potential anti-COVID-19 |
title_full_unstemmed | Monoclonal antibody as a potential anti-COVID-19 |
title_short | Monoclonal antibody as a potential anti-COVID-19 |
title_sort | monoclonal antibody as a potential anti-covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269943/ https://www.ncbi.nlm.nih.gov/pubmed/32534226 http://dx.doi.org/10.1016/j.biopha.2020.110337 |
work_keys_str_mv | AT jahanshahluleila monoclonalantibodyasapotentialanticovid19 AT rezaeinima monoclonalantibodyasapotentialanticovid19 |