Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation

Biology utilizes multiple strategies, including sequestration in lipid vesicles, to raise the rate and specificity of chemical reactions through increases in effective molarity of reactants. We show that micelle-assisted reaction can facilitate native chemical ligations (NCLs) between a peptide-thio...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Shuaijiang, Brea, Roberto J., Rudd, Andrew K., Moon, Stuart P., Pratt, Matthew R., Devaraj, Neal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270136/
https://www.ncbi.nlm.nih.gov/pubmed/32493905
http://dx.doi.org/10.1038/s41467-020-16595-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270136/
https://www.ncbi.nlm.nih.gov/pubmed/32493905
http://dx.doi.org/10.1038/s41467-020-16595-w

Ejemplares similares