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Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation
Biology utilizes multiple strategies, including sequestration in lipid vesicles, to raise the rate and specificity of chemical reactions through increases in effective molarity of reactants. We show that micelle-assisted reaction can facilitate native chemical ligations (NCLs) between a peptide-thio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270136/ https://www.ncbi.nlm.nih.gov/pubmed/32493905 http://dx.doi.org/10.1038/s41467-020-16595-w |