MicroRNAs in Sarcopenia: A Systematic Review

Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies ha...

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Detalles Bibliográficos
Autores principales: Yanai, Katsunori, Kaneko, Shohei, Ishii, Hiroki, Aomatsu, Akinori, Ito, Kiyonori, Hirai, Keiji, Ookawara, Susumu, Ishibashi, Kenichi, Morishita, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270169/
https://www.ncbi.nlm.nih.gov/pubmed/32549041
http://dx.doi.org/10.3389/fmed.2020.00180
Descripción
Sumario:Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.

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