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Preclinical safety and efficacy of 24R,25-dihydroxyvitamin D(3) or lactosylceramide treatment to enhance fracture repair

BACKGROUND/OBJECTIVE: Cyp24a1-null mice deficient in 24,25(OH)(2)D(3) display impaired callus formation during the endochondral phase of bone fracture repair. The 24,25(OH)(2)D(3) metabolite acted by binding to the TLC domain containing 3B isoform 2 (TLCD3B2, previously named FAM57B2) effector prote...

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Detalles Bibliográficos
Autores principales:	Martineau, Corine, Kaufmann, Martin, Arabian, Alice, Jones, Glenville, St-Arnaud, René
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Speaking Orthopaedic Society 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270532/ https://www.ncbi.nlm.nih.gov/pubmed/32518749 http://dx.doi.org/10.1016/j.jot.2020.03.013

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