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Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease

Invasive tracheobronchial aspergillosis (ITBA) complicated by nontuberculous mycobacteria (NTM) is rare. An 88-year-old man was admitted for hemoptysis. Bronchoscopy revealed bronchial ulcers, and a tissue biopsy showed Aspergillus fumigatus. He was diagnosed with ITBA, which improved with voriconaz...

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Autores principales: Kanai, Tomohiro, Samejima, Yumiko, Noda, Yoshimi, Kim, Sung-Ho, Tamura, Kanako, Umakoshi, Taisei, Shimizu, Kazunori, Kashiwa, Yozo, Morishita, Hiroshi, Ueda, Kayo, Kawahara, Kunimitsu, Yaguchi, Takashi, Matsuoka, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270761/
https://www.ncbi.nlm.nih.gov/pubmed/32009092
http://dx.doi.org/10.2169/internalmedicine.3827-19
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author Kanai, Tomohiro
Samejima, Yumiko
Noda, Yoshimi
Kim, Sung-Ho
Tamura, Kanako
Umakoshi, Taisei
Shimizu, Kazunori
Kashiwa, Yozo
Morishita, Hiroshi
Ueda, Kayo
Kawahara, Kunimitsu
Yaguchi, Takashi
Matsuoka, Hiroto
author_facet Kanai, Tomohiro
Samejima, Yumiko
Noda, Yoshimi
Kim, Sung-Ho
Tamura, Kanako
Umakoshi, Taisei
Shimizu, Kazunori
Kashiwa, Yozo
Morishita, Hiroshi
Ueda, Kayo
Kawahara, Kunimitsu
Yaguchi, Takashi
Matsuoka, Hiroto
author_sort Kanai, Tomohiro
collection PubMed
description Invasive tracheobronchial aspergillosis (ITBA) complicated by nontuberculous mycobacteria (NTM) is rare. An 88-year-old man was admitted for hemoptysis. Bronchoscopy revealed bronchial ulcers, and a tissue biopsy showed Aspergillus fumigatus. He was diagnosed with ITBA, which improved with voriconazole. During treatment, infiltrative shadows appeared in his lungs, and bronchoscopy was performed once again. A non-necrotic epithelioid granuloma and Mycobacterium intracellulare were detected in the biopsy specimen. He was diagnosed with NTM disease. It is important to note that tracheobronchial ulcers may cause hemoptysis and to identify the etiology and treat it appropriately when multiple bacteria are found.
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spelling pubmed-72707612020-06-09 Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease Kanai, Tomohiro Samejima, Yumiko Noda, Yoshimi Kim, Sung-Ho Tamura, Kanako Umakoshi, Taisei Shimizu, Kazunori Kashiwa, Yozo Morishita, Hiroshi Ueda, Kayo Kawahara, Kunimitsu Yaguchi, Takashi Matsuoka, Hiroto Intern Med Case Report Invasive tracheobronchial aspergillosis (ITBA) complicated by nontuberculous mycobacteria (NTM) is rare. An 88-year-old man was admitted for hemoptysis. Bronchoscopy revealed bronchial ulcers, and a tissue biopsy showed Aspergillus fumigatus. He was diagnosed with ITBA, which improved with voriconazole. During treatment, infiltrative shadows appeared in his lungs, and bronchoscopy was performed once again. A non-necrotic epithelioid granuloma and Mycobacterium intracellulare were detected in the biopsy specimen. He was diagnosed with NTM disease. It is important to note that tracheobronchial ulcers may cause hemoptysis and to identify the etiology and treat it appropriately when multiple bacteria are found. The Japanese Society of Internal Medicine 2020-02-01 2020-05-01 /pmc/articles/PMC7270761/ /pubmed/32009092 http://dx.doi.org/10.2169/internalmedicine.3827-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kanai, Tomohiro
Samejima, Yumiko
Noda, Yoshimi
Kim, Sung-Ho
Tamura, Kanako
Umakoshi, Taisei
Shimizu, Kazunori
Kashiwa, Yozo
Morishita, Hiroshi
Ueda, Kayo
Kawahara, Kunimitsu
Yaguchi, Takashi
Matsuoka, Hiroto
Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
title Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
title_full Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
title_fullStr Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
title_full_unstemmed Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
title_short Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
title_sort invasive tracheobronchial aspergillosis with bronchial ulcers complicated by nontuberculous mycobacterial disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270761/
https://www.ncbi.nlm.nih.gov/pubmed/32009092
http://dx.doi.org/10.2169/internalmedicine.3827-19
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