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Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease
Invasive tracheobronchial aspergillosis (ITBA) complicated by nontuberculous mycobacteria (NTM) is rare. An 88-year-old man was admitted for hemoptysis. Bronchoscopy revealed bronchial ulcers, and a tissue biopsy showed Aspergillus fumigatus. He was diagnosed with ITBA, which improved with voriconaz...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270761/ https://www.ncbi.nlm.nih.gov/pubmed/32009092 http://dx.doi.org/10.2169/internalmedicine.3827-19 |
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author | Kanai, Tomohiro Samejima, Yumiko Noda, Yoshimi Kim, Sung-Ho Tamura, Kanako Umakoshi, Taisei Shimizu, Kazunori Kashiwa, Yozo Morishita, Hiroshi Ueda, Kayo Kawahara, Kunimitsu Yaguchi, Takashi Matsuoka, Hiroto |
author_facet | Kanai, Tomohiro Samejima, Yumiko Noda, Yoshimi Kim, Sung-Ho Tamura, Kanako Umakoshi, Taisei Shimizu, Kazunori Kashiwa, Yozo Morishita, Hiroshi Ueda, Kayo Kawahara, Kunimitsu Yaguchi, Takashi Matsuoka, Hiroto |
author_sort | Kanai, Tomohiro |
collection | PubMed |
description | Invasive tracheobronchial aspergillosis (ITBA) complicated by nontuberculous mycobacteria (NTM) is rare. An 88-year-old man was admitted for hemoptysis. Bronchoscopy revealed bronchial ulcers, and a tissue biopsy showed Aspergillus fumigatus. He was diagnosed with ITBA, which improved with voriconazole. During treatment, infiltrative shadows appeared in his lungs, and bronchoscopy was performed once again. A non-necrotic epithelioid granuloma and Mycobacterium intracellulare were detected in the biopsy specimen. He was diagnosed with NTM disease. It is important to note that tracheobronchial ulcers may cause hemoptysis and to identify the etiology and treat it appropriately when multiple bacteria are found. |
format | Online Article Text |
id | pubmed-7270761 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-72707612020-06-09 Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease Kanai, Tomohiro Samejima, Yumiko Noda, Yoshimi Kim, Sung-Ho Tamura, Kanako Umakoshi, Taisei Shimizu, Kazunori Kashiwa, Yozo Morishita, Hiroshi Ueda, Kayo Kawahara, Kunimitsu Yaguchi, Takashi Matsuoka, Hiroto Intern Med Case Report Invasive tracheobronchial aspergillosis (ITBA) complicated by nontuberculous mycobacteria (NTM) is rare. An 88-year-old man was admitted for hemoptysis. Bronchoscopy revealed bronchial ulcers, and a tissue biopsy showed Aspergillus fumigatus. He was diagnosed with ITBA, which improved with voriconazole. During treatment, infiltrative shadows appeared in his lungs, and bronchoscopy was performed once again. A non-necrotic epithelioid granuloma and Mycobacterium intracellulare were detected in the biopsy specimen. He was diagnosed with NTM disease. It is important to note that tracheobronchial ulcers may cause hemoptysis and to identify the etiology and treat it appropriately when multiple bacteria are found. The Japanese Society of Internal Medicine 2020-02-01 2020-05-01 /pmc/articles/PMC7270761/ /pubmed/32009092 http://dx.doi.org/10.2169/internalmedicine.3827-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kanai, Tomohiro Samejima, Yumiko Noda, Yoshimi Kim, Sung-Ho Tamura, Kanako Umakoshi, Taisei Shimizu, Kazunori Kashiwa, Yozo Morishita, Hiroshi Ueda, Kayo Kawahara, Kunimitsu Yaguchi, Takashi Matsuoka, Hiroto Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease |
title | Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease |
title_full | Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease |
title_fullStr | Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease |
title_full_unstemmed | Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease |
title_short | Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease |
title_sort | invasive tracheobronchial aspergillosis with bronchial ulcers complicated by nontuberculous mycobacterial disease |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270761/ https://www.ncbi.nlm.nih.gov/pubmed/32009092 http://dx.doi.org/10.2169/internalmedicine.3827-19 |
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