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Systemic Melioidosis With Ruptured Splenic Abscess

Melioidosis is a severe systemic disease caused by the bacterium Burkholderia pseudomallei, commonly found in soil, ground water, and ponds of endemic regions. It is transmitted to humans via percutaneous inoculation while working in these areas without protective clothing and footwear giving rise t...

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Autores principales: Chinnakkulam Kandhasamy, Sakthivel, Elamurugan, TP, Naik, Debasis, Rohith, Gorrepati, Nelamangala Ramakrishnaiah, Vishnu Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270831/
https://www.ncbi.nlm.nih.gov/pubmed/32509481
http://dx.doi.org/10.7759/cureus.7956
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author Chinnakkulam Kandhasamy, Sakthivel
Elamurugan, TP
Naik, Debasis
Rohith, Gorrepati
Nelamangala Ramakrishnaiah, Vishnu Prasad
author_facet Chinnakkulam Kandhasamy, Sakthivel
Elamurugan, TP
Naik, Debasis
Rohith, Gorrepati
Nelamangala Ramakrishnaiah, Vishnu Prasad
author_sort Chinnakkulam Kandhasamy, Sakthivel
collection PubMed
description Melioidosis is a severe systemic disease caused by the bacterium Burkholderia pseudomallei, commonly found in soil, ground water, and ponds of endemic regions. It is transmitted to humans via percutaneous inoculation while working in these areas without protective clothing and footwear giving rise to the disease which has a high case fatality rate. It has a wide range of clinical manifestations, varying from asymptomatic infection to localized abscess formation to fulminating disease with multiple organ involvement and even death. Currently, there are no known pathognomonic features or specific criteria which can lead to a confident diagnosis of melioidosis. The gold standard diagnostic test is culture sensitivity of blood, pus, or bodily fluids, which itself has a low sensitivity. Imaging findings are not specific and can mimic other bacterial infection. However, awareness of these radiographic manifestations in multiple organs can raise the possibility of diagnosis and lead to more early proper treatment and thereby lower the high mortality associated with this disease. We here present a rare case of systemic melioidosis with ruptured splenic abscess managed laboriously with antibiotics and splenectomy and wish to review the literature.
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spelling pubmed-72708312020-06-05 Systemic Melioidosis With Ruptured Splenic Abscess Chinnakkulam Kandhasamy, Sakthivel Elamurugan, TP Naik, Debasis Rohith, Gorrepati Nelamangala Ramakrishnaiah, Vishnu Prasad Cureus Internal Medicine Melioidosis is a severe systemic disease caused by the bacterium Burkholderia pseudomallei, commonly found in soil, ground water, and ponds of endemic regions. It is transmitted to humans via percutaneous inoculation while working in these areas without protective clothing and footwear giving rise to the disease which has a high case fatality rate. It has a wide range of clinical manifestations, varying from asymptomatic infection to localized abscess formation to fulminating disease with multiple organ involvement and even death. Currently, there are no known pathognomonic features or specific criteria which can lead to a confident diagnosis of melioidosis. The gold standard diagnostic test is culture sensitivity of blood, pus, or bodily fluids, which itself has a low sensitivity. Imaging findings are not specific and can mimic other bacterial infection. However, awareness of these radiographic manifestations in multiple organs can raise the possibility of diagnosis and lead to more early proper treatment and thereby lower the high mortality associated with this disease. We here present a rare case of systemic melioidosis with ruptured splenic abscess managed laboriously with antibiotics and splenectomy and wish to review the literature. Cureus 2020-05-04 /pmc/articles/PMC7270831/ /pubmed/32509481 http://dx.doi.org/10.7759/cureus.7956 Text en Copyright © 2020, Chinnakkulam Kandhasamy et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Chinnakkulam Kandhasamy, Sakthivel
Elamurugan, TP
Naik, Debasis
Rohith, Gorrepati
Nelamangala Ramakrishnaiah, Vishnu Prasad
Systemic Melioidosis With Ruptured Splenic Abscess
title Systemic Melioidosis With Ruptured Splenic Abscess
title_full Systemic Melioidosis With Ruptured Splenic Abscess
title_fullStr Systemic Melioidosis With Ruptured Splenic Abscess
title_full_unstemmed Systemic Melioidosis With Ruptured Splenic Abscess
title_short Systemic Melioidosis With Ruptured Splenic Abscess
title_sort systemic melioidosis with ruptured splenic abscess
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270831/
https://www.ncbi.nlm.nih.gov/pubmed/32509481
http://dx.doi.org/10.7759/cureus.7956
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