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Subclinical atherosclerosis: how and when to treat it?

Atherosclerosis is a condition characterized by a long, initial, asymptomatic phase. Progression of disease could lead to acute coronary events, such as acute myocardial infarction, unstable angina, or sudden cardiac death. However, there are imaging techniques, namely vascular echography and assess...

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Detalles Bibliográficos
Autores principales: Gatto, Laura, Prati, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270961/
https://www.ncbi.nlm.nih.gov/pubmed/32523447
http://dx.doi.org/10.1093/eurheartj/suaa068
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author Gatto, Laura
Prati, Francesco
author_facet Gatto, Laura
Prati, Francesco
author_sort Gatto, Laura
collection PubMed
description Atherosclerosis is a condition characterized by a long, initial, asymptomatic phase. Progression of disease could lead to acute coronary events, such as acute myocardial infarction, unstable angina, or sudden cardiac death. However, there are imaging techniques, namely vascular echography and assessment of coronary calcium, capable to make the diagnosis of atherosclerosis at an early stage. There are several studies demonstrating the ability of statins to delay, and in some situation even revert the progression of this condition. Subclinical atherosclerosis is highly prevalent in people with optimal control of the risk factors, and the imaging techniques have been shown to provide an added value over the traditional risk factors: by identifying directly the condition, these techniques allow the reclassification of low-risk to intermediate- or high-risk subjects, thus directing the primary prevention therapeutic strategies, based on high efficacy statins, aimed at delaying or reversing the progression of the disease.
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spelling pubmed-72709612020-06-09 Subclinical atherosclerosis: how and when to treat it? Gatto, Laura Prati, Francesco Eur Heart J Suppl Articles Atherosclerosis is a condition characterized by a long, initial, asymptomatic phase. Progression of disease could lead to acute coronary events, such as acute myocardial infarction, unstable angina, or sudden cardiac death. However, there are imaging techniques, namely vascular echography and assessment of coronary calcium, capable to make the diagnosis of atherosclerosis at an early stage. There are several studies demonstrating the ability of statins to delay, and in some situation even revert the progression of this condition. Subclinical atherosclerosis is highly prevalent in people with optimal control of the risk factors, and the imaging techniques have been shown to provide an added value over the traditional risk factors: by identifying directly the condition, these techniques allow the reclassification of low-risk to intermediate- or high-risk subjects, thus directing the primary prevention therapeutic strategies, based on high efficacy statins, aimed at delaying or reversing the progression of the disease. Oxford University Press 2020-06 2020-03-24 /pmc/articles/PMC7270961/ /pubmed/32523447 http://dx.doi.org/10.1093/eurheartj/suaa068 Text en Published on behalf of the European Society of Cardiology. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Articles
Gatto, Laura
Prati, Francesco
Subclinical atherosclerosis: how and when to treat it?
title Subclinical atherosclerosis: how and when to treat it?
title_full Subclinical atherosclerosis: how and when to treat it?
title_fullStr Subclinical atherosclerosis: how and when to treat it?
title_full_unstemmed Subclinical atherosclerosis: how and when to treat it?
title_short Subclinical atherosclerosis: how and when to treat it?
title_sort subclinical atherosclerosis: how and when to treat it?
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270961/
https://www.ncbi.nlm.nih.gov/pubmed/32523447
http://dx.doi.org/10.1093/eurheartj/suaa068
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