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Long-term injury after Takotsubo syndrome (stress cardiomyopathy)

Takotsubo syndrome is a clinical condition characterized by transient impairment of left ventricular contractility, in association with symptoms, increase in indices of myocardial necrosis, as well as electrocardiographic changes, but without a coronary culprit lesion, and often after a significant...

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Autores principales: Vassiliki’ Coutsoumbas, Gloria, Gallo, Pamela, Zagnoni, Silvia, Di Pasquale, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270968/
https://www.ncbi.nlm.nih.gov/pubmed/32523444
http://dx.doi.org/10.1093/eurheartj/suaa065
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author Vassiliki’ Coutsoumbas, Gloria
Gallo, Pamela
Zagnoni, Silvia
Di Pasquale, Giuseppe
author_facet Vassiliki’ Coutsoumbas, Gloria
Gallo, Pamela
Zagnoni, Silvia
Di Pasquale, Giuseppe
author_sort Vassiliki’ Coutsoumbas, Gloria
collection PubMed
description Takotsubo syndrome is a clinical condition characterized by transient impairment of left ventricular contractility, in association with symptoms, increase in indices of myocardial necrosis, as well as electrocardiographic changes, but without a coronary culprit lesion, and often after a significant psychological or physical stress. Albeit very similar to acute coronary syndrome (ACS) as far as presentation and clinical course, Takotsubo syndrome was considered, up until recently, a condition with very favourable long-term prognosis, in view of the frequent complete functional recovery. More recently, several retrospective observational studies as well as registers, unexpectedly called attention to a significant incidence of major adverse cardiovascular events, not limited to the recovery period but also during the long-term follow-up, in a way very similar to the outcome of patients after ACS. Several negative prognostic factors have been isolated, such as physical stress as trigger of the condition, the presence of severe left ventricular dysfunction, and the consequent cardiogenic shock during the acute phase. These factors are able to classify better the patient’s prognosis, both in the short- and long-term, and identify patients requiring a more stringent clinical follow-up, considering the higher likelihood of adverse cardiovascular events.
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spelling pubmed-72709682020-06-09 Long-term injury after Takotsubo syndrome (stress cardiomyopathy) Vassiliki’ Coutsoumbas, Gloria Gallo, Pamela Zagnoni, Silvia Di Pasquale, Giuseppe Eur Heart J Suppl Articles Takotsubo syndrome is a clinical condition characterized by transient impairment of left ventricular contractility, in association with symptoms, increase in indices of myocardial necrosis, as well as electrocardiographic changes, but without a coronary culprit lesion, and often after a significant psychological or physical stress. Albeit very similar to acute coronary syndrome (ACS) as far as presentation and clinical course, Takotsubo syndrome was considered, up until recently, a condition with very favourable long-term prognosis, in view of the frequent complete functional recovery. More recently, several retrospective observational studies as well as registers, unexpectedly called attention to a significant incidence of major adverse cardiovascular events, not limited to the recovery period but also during the long-term follow-up, in a way very similar to the outcome of patients after ACS. Several negative prognostic factors have been isolated, such as physical stress as trigger of the condition, the presence of severe left ventricular dysfunction, and the consequent cardiogenic shock during the acute phase. These factors are able to classify better the patient’s prognosis, both in the short- and long-term, and identify patients requiring a more stringent clinical follow-up, considering the higher likelihood of adverse cardiovascular events. Oxford University Press 2020-06 2020-03-24 /pmc/articles/PMC7270968/ /pubmed/32523444 http://dx.doi.org/10.1093/eurheartj/suaa065 Text en Published on behalf of the European Society of Cardiology. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Articles
Vassiliki’ Coutsoumbas, Gloria
Gallo, Pamela
Zagnoni, Silvia
Di Pasquale, Giuseppe
Long-term injury after Takotsubo syndrome (stress cardiomyopathy)
title Long-term injury after Takotsubo syndrome (stress cardiomyopathy)
title_full Long-term injury after Takotsubo syndrome (stress cardiomyopathy)
title_fullStr Long-term injury after Takotsubo syndrome (stress cardiomyopathy)
title_full_unstemmed Long-term injury after Takotsubo syndrome (stress cardiomyopathy)
title_short Long-term injury after Takotsubo syndrome (stress cardiomyopathy)
title_sort long-term injury after takotsubo syndrome (stress cardiomyopathy)
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270968/
https://www.ncbi.nlm.nih.gov/pubmed/32523444
http://dx.doi.org/10.1093/eurheartj/suaa065
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