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Lewis Acid-Catalyzed Enantioselective Friedel–Crafts Alkylation of Pyrrole in Water

[Image: see text] Highly enantioselective Friedel–Crafts alkylation of pyrroles with 2-enoyl-pyridine N-oxides in water/chloroform (10:1) was developed under catalysis of Lewis acid. The Friedel–Crafts alkylation products can be obtained in high yields and excellent enantioselectivities. Moreover, s...

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Detalles Bibliográficos
Autores principales: Sun, Jianan, Gui, Yang, Huang, Yekai, Li, Jindong, Zha, Zhenggen, Yang, Yu, Wang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271029/
https://www.ncbi.nlm.nih.gov/pubmed/32548375
http://dx.doi.org/10.1021/acsomega.9b04115