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Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology
Small molecule polyamines are abundant in all life forms and participate in diverse aspects of cell growth and differentiation. Spermidine/spermine acetyltransferase (SAT1) is the rate-limiting enzyme in polyamine catabolism and a primary genetic risk factor for suicidality. Here, using genome-wide...
Autores principales: | Dhara, Madhurima, Matta, Jose A., Lei, Min, Knowland, Daniel, Yu, Hong, Gu, Shenyan, Bredt, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271128/ https://www.ncbi.nlm.nih.gov/pubmed/32493979 http://dx.doi.org/10.1038/s41467-020-16629-3 |
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