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Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology

Small molecule polyamines are abundant in all life forms and participate in diverse aspects of cell growth and differentiation. Spermidine/spermine acetyltransferase (SAT1) is the rate-limiting enzyme in polyamine catabolism and a primary genetic risk factor for suicidality. Here, using genome-wide...

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Detalles Bibliográficos
Autores principales: Dhara, Madhurima, Matta, Jose A., Lei, Min, Knowland, Daniel, Yu, Hong, Gu, Shenyan, Bredt, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271128/
https://www.ncbi.nlm.nih.gov/pubmed/32493979
http://dx.doi.org/10.1038/s41467-020-16629-3

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