COVID-19 vaccines: neutralizing antibodies and the alum advantage

Achieving high levels of neutralizing antibodies to the spike protein of SARS-CoV-2 in a safe manner is likely to be crucial for an effective vaccine. Here, we propose that aluminium-based adjuvants might hold the key to this.

Detalles Bibliográficos
Autores principales: Hotez, Peter J., Corry, David B., Strych, Ulrich, Bottazzi, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271131/
https://www.ncbi.nlm.nih.gov/pubmed/32499636
http://dx.doi.org/10.1038/s41577-020-0358-6
Descripción
Sumario:Achieving high levels of neutralizing antibodies to the spike protein of SARS-CoV-2 in a safe manner is likely to be crucial for an effective vaccine. Here, we propose that aluminium-based adjuvants might hold the key to this.

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