Cargando…
IFT proteins interact with HSET to promote supernumerary centrosome clustering in mitosis
Centrosome amplification is a hallmark of cancer, and centrosome clustering is essential for cancer cell survival. The mitotic kinesin HSET is an essential contributor to this process. Recent studies have highlighted novel functions for intraflagellar transport (IFT) proteins in regulating motors an...
Autores principales: | Vitre, Benjamin, Taulet, Nicolas, Guesdon, Audrey, Douanier, Audrey, Dosdane, Aurelie, Cisneros, Melanie, Maurin, Justine, Hettinger, Sabrina, Anguille, Christelle, Taschner, Michael, Lorentzen, Esben, Delaval, Benedicte |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271317/ https://www.ncbi.nlm.nih.gov/pubmed/32270908 http://dx.doi.org/10.15252/embr.201949234 |
Ejemplares similares
-
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning
por: Taulet, Nicolas, et al.
Publicado: (2017) -
IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles
por: Taulet, Nicolas, et al.
Publicado: (2019) -
Non-ciliary Roles of IFT Proteins in Cell Division and Polycystic Kidney Diseases
por: Vitre, Benjamin, et al.
Publicado: (2020) -
Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes
por: Watts, Ciorsdaidh A., et al.
Publicado: (2013) -
The cilia protein IFT88 is required for spindle orientation in mitosis
por: Delaval, Benedicte, et al.
Publicado: (2011)