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Metabolic energy sensing by mammalian CLC anion/proton exchangers

CLC anion/proton exchangers control the pH and [Cl(−)] of the endolysosomal system that is essential for cellular nutrient uptake. Here, we use heterologous expression and whole‐cell electrophysiology to investigate the regulation of the CLC isoforms ClC‐3, ClC‐4, and ClC‐5 by the adenylic system co...

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Detalles Bibliográficos
Autores principales:	Grieschat, Matthias, Guzman, Raul E, Langschwager, Katharina, Fahlke, Christoph, Alekov, Alexi K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271328/ https://www.ncbi.nlm.nih.gov/pubmed/32390228 http://dx.doi.org/10.15252/embr.201947872

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