Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function

BACKGROUND: Epithin/PRSS14, a type II transmembrane serine protease, is an emerging target of cancer therapy because of its critical roles in tumor progression and metastasis. In many circumstances, the protease, through its ectodomain shedding, exists as a soluble form and performs its proteolytic...

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Detalles Bibliográficos
Autores principales: Cho, Youngkyung, Kim, Sang Bum, Kim, Jiyoon, Pham, An Vuong Quynh, Yoon, Min Ji, Park, Jeong Hwan, Hwang, Ki-Tae, Park, Dongeun, Cho, Yongcheol, Kim, Moon Gyo, Kim, Chungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271384/
https://www.ncbi.nlm.nih.gov/pubmed/32493324
http://dx.doi.org/10.1186/s12915-020-00787-3

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