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Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants
BACKGROUND: Cutaneous leishmaniasis (CL), being among the neglected tropical diseases, catches little attention despite its considerable influence. This study aimed at estimating the prevalence and associated factors of CL in Boru Meda Hospital, Dessie town, north-central Ethiopia. METHODS: Medical...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271444/ https://www.ncbi.nlm.nih.gov/pubmed/32518497 http://dx.doi.org/10.1186/s41182-020-00231-w |
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author | Eshetu, Belayneh Mamo, Hassen |
author_facet | Eshetu, Belayneh Mamo, Hassen |
author_sort | Eshetu, Belayneh |
collection | PubMed |
description | BACKGROUND: Cutaneous leishmaniasis (CL), being among the neglected tropical diseases, catches little attention despite its considerable influence. This study aimed at estimating the prevalence and associated factors of CL in Boru Meda Hospital, Dessie town, north-central Ethiopia. METHODS: Medical records of patients who attended the Dermatology Department of the Hospital in 2012–May 2018 were assessed. In addition, dermatological patients who were visiting the hospital during the data collection period (November 2017–May 2018) were interviewed to capture socio-demographic, environmental variables, and related factors. The source population was individuals who visited the hospital for skin problems in the stated years and CL positives were the targets. The association between CL and its determinants was tested by logistic regression. RESULTS: CL prevalence was 1.5% showing increasing trend with the year of examination. Localized, diffused, and mucosal CL was evident across the years. Dessie town had the highest prevalence, 291 (32.8%) patients out of 888 cases. The number of examined (29,701) and positives (543, 1.8%) for males was comparable with females, 28,459 and 345 (1.2%), respectively, increasing with age but without significant difference. Dessie town residence (adjusted odds ratio (AOR) 12.2, 95% confidence interval (CI) 2.2–18.6, p = 0.01), no bed net (AOR 9.9, 95% CI 2.7–16.7, p < 0.01), nearby irrigation (AOR 8.1, 95% CI 1.9–12.4, p < 0.01), and travel to CL endemic areas (AOR 13.9, 95% CI 4.4–14.3, p < 0.01) were significantly associated with CL. CONCLUSION: CL is a growing health problem in Dessie and its surroundings. Known risk factors prevail. Comprehensive parasitological, entomological, and social studies are warranted to better manage the disease. |
format | Online Article Text |
id | pubmed-7271444 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-72714442020-06-08 Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants Eshetu, Belayneh Mamo, Hassen Trop Med Health Research BACKGROUND: Cutaneous leishmaniasis (CL), being among the neglected tropical diseases, catches little attention despite its considerable influence. This study aimed at estimating the prevalence and associated factors of CL in Boru Meda Hospital, Dessie town, north-central Ethiopia. METHODS: Medical records of patients who attended the Dermatology Department of the Hospital in 2012–May 2018 were assessed. In addition, dermatological patients who were visiting the hospital during the data collection period (November 2017–May 2018) were interviewed to capture socio-demographic, environmental variables, and related factors. The source population was individuals who visited the hospital for skin problems in the stated years and CL positives were the targets. The association between CL and its determinants was tested by logistic regression. RESULTS: CL prevalence was 1.5% showing increasing trend with the year of examination. Localized, diffused, and mucosal CL was evident across the years. Dessie town had the highest prevalence, 291 (32.8%) patients out of 888 cases. The number of examined (29,701) and positives (543, 1.8%) for males was comparable with females, 28,459 and 345 (1.2%), respectively, increasing with age but without significant difference. Dessie town residence (adjusted odds ratio (AOR) 12.2, 95% confidence interval (CI) 2.2–18.6, p = 0.01), no bed net (AOR 9.9, 95% CI 2.7–16.7, p < 0.01), nearby irrigation (AOR 8.1, 95% CI 1.9–12.4, p < 0.01), and travel to CL endemic areas (AOR 13.9, 95% CI 4.4–14.3, p < 0.01) were significantly associated with CL. CONCLUSION: CL is a growing health problem in Dessie and its surroundings. Known risk factors prevail. Comprehensive parasitological, entomological, and social studies are warranted to better manage the disease. BioMed Central 2020-06-03 /pmc/articles/PMC7271444/ /pubmed/32518497 http://dx.doi.org/10.1186/s41182-020-00231-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Eshetu, Belayneh Mamo, Hassen Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants |
title | Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants |
title_full | Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants |
title_fullStr | Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants |
title_full_unstemmed | Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants |
title_short | Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants |
title_sort | cutaneous leishmaniasis in north-central ethiopia: trend, clinical forms, geographic distribution, and determinants |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271444/ https://www.ncbi.nlm.nih.gov/pubmed/32518497 http://dx.doi.org/10.1186/s41182-020-00231-w |
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