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Glycoprotein Ib clustering in platelets can be inhibited by α-linolenic acid as revealed by cryo-electron tomography
Platelet adhesion to the sub-endothelial matrix and damaged endothelium occurs through a multi-step process mediated in the initial phase by glycoprotein Ib binding to von Willebrand factor (vWF), which leads to the subsequent formation of a platelet plug. The plant-derived ω-3 fatty acid α-linoleni...
Autores principales: | Stivala, Simona, Sorrentino, Simona, Gobbato, Sara, Bonetti, Nicole R., Camici, Giovanni G., Lüscher, Thomas F., Medalia, Ohad, Beer, Jürg H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271563/ https://www.ncbi.nlm.nih.gov/pubmed/31439672 http://dx.doi.org/10.3324/haematol.2019.220988 |
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