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The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy

The introduction of anti-CD20 monoclonal antibodies such as rituximab, ofatumumab, or obinutuzumab improved the therapy of B-cell malignancies even though the precise physiological role and regulation of CD20 remains unclear. Furthermore, CD20 expression is highly variable between different B-cell m...

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Detalles Bibliográficos
Autores principales: Pavlasova, Gabriela, Mraz, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271567/
https://www.ncbi.nlm.nih.gov/pubmed/32482755
http://dx.doi.org/10.3324/haematol.2019.243543