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The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy
The introduction of anti-CD20 monoclonal antibodies such as rituximab, ofatumumab, or obinutuzumab improved the therapy of B-cell malignancies even though the precise physiological role and regulation of CD20 remains unclear. Furthermore, CD20 expression is highly variable between different B-cell m...
Autores principales: | Pavlasova, Gabriela, Mraz, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271567/ https://www.ncbi.nlm.nih.gov/pubmed/32482755 http://dx.doi.org/10.3324/haematol.2019.243543 |
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