D’ domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding

In the complex with von Willebrand factor (VWF) factor VIII (FVIII) is protected from rapid clearance from circulation. Although it has been established that the FVIII binding site resides in the N-terminal D’-D3 domains of VWF, detailed information about the amino acid regions that contribute to FV...

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Detalles Bibliográficos
Autores principales: Przeradzka, Małgorzata A., van Galen, Josse, Ebberink, Eduard H. T. M., Hoogendijk, Arie J., van der Zwaan, Carmen, Mertens, Koen, van den Biggelaar, Maartje, Meijer, Alexander B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271574/
https://www.ncbi.nlm.nih.gov/pubmed/31558672
http://dx.doi.org/10.3324/haematol.2019.221994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271574/
https://www.ncbi.nlm.nih.gov/pubmed/31558672
http://dx.doi.org/10.3324/haematol.2019.221994

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