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Genetic platelet depletion is superior in platelet transfusion compared to current models
Genetically modified mice have advanced our knowledge on platelets in hemostasis and beyond tremendously. However, mouse models harbor certain limitations, including availability of platelet specific transgenic strains, and off-target effects on other cell types. Transfusion of genetically modified...
Autores principales: | Salzmann, Manuel, Schrottmaier, Waltraud C., Kral-Pointner, Julia B., Mussbacher, Marion, Volz, Julia, Hoesel, Bastian, Moser, Bernhard, Bleichert, Sonja, Morava, Susanne, Nieswandt, Bernhard, Schmid, Johannes A., Assinger, Alice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271594/ https://www.ncbi.nlm.nih.gov/pubmed/31537686 http://dx.doi.org/10.3324/haematol.2019.222448 |
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