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Temozolomide and oral etoposide in children with recurrent malignant brain tumors

Despite advances in the treatment of brain tumors, the prognosis of children with recurrent malignant brain tumors remains poor. Etoposide (VP-16), an inhibitor of nuclear enzyme deoxyribonucleic acid (DNA)-topoisomerase II, has shown activity in brain tumors. Its efficacy appears schedule dependent...

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Detalles Bibliográficos
Autores principales:	Ruggiero, Antonio, Ariano, Anna, Triarico, Silvia, Capozza, Michele Antonio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Attinà, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioExcel Publishing Ltd 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271709/ https://www.ncbi.nlm.nih.gov/pubmed/32547627 http://dx.doi.org/10.7573/dic.2020-3-1

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