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Bayesian modeling reveals metabolite‐dependent ultrasensitivity in the cyanobacterial circadian clock

Mathematical models can enable a predictive understanding of mechanism in cell biology by quantitatively describing complex networks of interactions, but such models are often poorly constrained by available data. Owing to its relative biochemical simplicity, the core circadian oscillator in Synecho...

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Detalles Bibliográficos
Autores principales: Hong, Lu, Lavrentovich, Danylo O, Chavan, Archana, Leypunskiy, Eugene, Li, Eileen, Matthews, Charles, LiWang, Andy, Rust, Michael J, Dinner, Aaron R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271899/
https://www.ncbi.nlm.nih.gov/pubmed/32496641
http://dx.doi.org/10.15252/msb.20199355