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Lnc-ITSN1-2, Derived From RNA Sequencing, Correlates With Increased Disease Risk, Activity and Promotes CD4(+) T Cell Activation, Proliferation and Th1/Th17 Cell Differentiation by Serving as a ceRNA for IL-23R via Sponging miR-125a in Inflammatory Bowel Disease

Background: This study aimed to investigate long-non-coding RNA (lncRNA) expression profiles and the correlation of lnc-ITSN1-2 expression with disease risk, activity and inflammation, and its influence on CD4(+) T cell activation, proliferation, and differentiation of inflammatory bowel disease (IB...

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Detalles Bibliográficos
Autores principales: Nie, Jiayan, Zhao, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271921/
https://www.ncbi.nlm.nih.gov/pubmed/32547537
http://dx.doi.org/10.3389/fimmu.2020.00852