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The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting
A large fraction of epigenetically silent heterochromatin is anchored to the nuclear periphery via ‘tethering proteins’ that function to bridge heterochromatin and the nuclear membrane or nuclear lamina. We previously identified a human tethering protein, PRR14, that binds heterochromatin through an...
Autores principales: | Dunlevy, Kelly L., Medvedeva, Valentina, Wilson, Jade E., Hoque, Mohammed, Pellegrin, Trinity, Maynard, Adam, Kremp, Madison M., Wasserman, Jason S., Poleshko, Andrey, Katz, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272351/ https://www.ncbi.nlm.nih.gov/pubmed/32317397 http://dx.doi.org/10.1242/jcs.240416 |
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