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A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture

Mouse mammary organ culture (MMOC) is used to evaluate the efficacy of chemopreventive agents against the development of carcinogen-induced preneoplastic lesions and is highly correlative to in vivo carcinogenesis models. Here, we developed a new ex vivo MMOC model, by introducing human breast cance...

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Detalles Bibliográficos
Autores principales: Gupta, Akash, Gupta, Geetanjali, Mehta, Rajeshwari R., Ivancic, David Z., Walker, Rashidra R., Patel, Jankiben R., Gallegos, Karen M., Davidson, A. Michael, Khan, Seema A., Mehta, Rajendra G., Tilghman, Syreeta L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272353/
https://www.ncbi.nlm.nih.gov/pubmed/32366373
http://dx.doi.org/10.1242/bio.051649