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A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture
Mouse mammary organ culture (MMOC) is used to evaluate the efficacy of chemopreventive agents against the development of carcinogen-induced preneoplastic lesions and is highly correlative to in vivo carcinogenesis models. Here, we developed a new ex vivo MMOC model, by introducing human breast cance...
Autores principales: | Gupta, Akash, Gupta, Geetanjali, Mehta, Rajeshwari R., Ivancic, David Z., Walker, Rashidra R., Patel, Jankiben R., Gallegos, Karen M., Davidson, A. Michael, Khan, Seema A., Mehta, Rajendra G., Tilghman, Syreeta L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272353/ https://www.ncbi.nlm.nih.gov/pubmed/32366373 http://dx.doi.org/10.1242/bio.051649 |
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