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Relevance of physicochemical properties and functional pharmacology data to predict the clinical safety profile of direct oral anticoagulants
Direct oral anticoagulants (DOACs) have rapidly become the drug class of choice for anticoagulation therapy in secondary care. It is known that gastrointestinal hemorrhage are potential side effects of the DOAC drug class. In this study we have investigated the relevance of molecular structure and o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272392/ https://www.ncbi.nlm.nih.gov/pubmed/32500654 http://dx.doi.org/10.1002/prp2.603 |