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Relevance of physicochemical properties and functional pharmacology data to predict the clinical safety profile of direct oral anticoagulants

Direct oral anticoagulants (DOACs) have rapidly become the drug class of choice for anticoagulation therapy in secondary care. It is known that gastrointestinal hemorrhage are potential side effects of the DOAC drug class. In this study we have investigated the relevance of molecular structure and o...

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Detalles Bibliográficos
Autores principales: Ferro, Charles J., Solkhon, Fay, Jalal, Zahraa, Al‐Hamid, Abdullah M., Jones, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272392/
https://www.ncbi.nlm.nih.gov/pubmed/32500654
http://dx.doi.org/10.1002/prp2.603