Cargando…

Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers

Tumor-promoting inflammation is a hallmark of cancer and is highly associated with tumor progression, angiogenesis, and metastasis. Tumor-associated macrophages (TAMs) are major drivers of tumor-promoting inflammation, but due to the complexity of the tumor microenvironment, the detailed regulatory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cho, Sung-Yup, Oh, Yumi, Jeong, Eui Man, Park, Sanghui, Lee, Dakeun, Wang, Xiaorui, Zeng, Qiqi, Qin, Hongyu, Hu, Fang, Gong, Hui, Liu, Xi, Zhang, Guanjun, Na, Deukchae, Lee, Jieun, Chae, Jeesoo, Suh, Yun-Suhk, Kong, Seong-Ho, Lee, Hyuk-Joon, Kim, Jong-Il, Park, Hansoo, Zhang, Chengsheng, Yang, Han-Kwang, Lee, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272405/ https://www.ncbi.nlm.nih.gov/pubmed/32467608 http://dx.doi.org/10.1038/s12276-020-0444-7

Ejemplares similares

Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts
por: Na, Deukchae, et al.
Publicado: (2021)

High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients
por: Cho, Sung-Yup, et al.
Publicado: (2017)

Clinical Significance of Variable Histomorphologic Findings Related to Mucosal Inflammation in Negative Appendectomy
por: Choi, Euno, et al.
Publicado: (2021)

Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein–protein interactions of the fused protein
por: Kim, Hyo-Jun, et al.
Publicado: (2021)

Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis
por: Jeong, Eui Man, et al.
Publicado: (2016)

Endoplasmic reticulum stress activates transglutaminase 2 leading to protein aggregation
por: LEE, JIN-HAENG, et al.
Publicado: (2014)

Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer
por: Lee, Jieun, et al.
Publicado: (2020)

Comprehensive Analysis of Alternative Splicing in Gastric Cancer Identifies Epithelial–Mesenchymal Transition Subtypes Associated with Survival
por: Jun, Yukyung, et al.
Publicado: (2022)

Effects of Transglutaminase 2 Inhibition on Ventilator-Induced Lung Injury
por: Suh, In Bum, et al.
Publicado: (2014)

Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs
por: Cho, Sung-Yup, et al.
Publicado: (2020)

Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity
por: Ha, Hyun Ji, et al.
Publicado: (2018)

Intimal Hyperplasia in Loop-Injured Carotid Arteries Is Attenuated in Transglutaminase 2-Null Mice
por: Min, Seung-Kee, et al.
Publicado: (2014)

Proximal Anterior-Antrum Posterior (PAAP) Overlapping Anastomosis in Minimally Invasive Pylorus-Preserving Gastrectomy for Early Gastric Cancer Located in the High Body and Posterior Wall of the Stomach
por: Park, Ji-Hyeon, et al.
Publicado: (2020)

Risk Factors of Microscopic Invasion in Early Gastric Cancer
por: Choi, Jong-Ho, et al.
Publicado: (2017)

A Novel Therapeutic Target in Inflammatory Uveitis: Transglutaminase 2 Inhibitor
por: Sohn, Joonhong, et al.
Publicado: (2010)

Comparison between laparoscopic pylorus-preserving gastrectomy and laparoscopic distal gastrectomy for overweight patients with early gastric cancer
por: Lee, Hwa-Jeong, et al.
Publicado: (2023)

Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2
por: Jeong, Eui Man, et al.
Publicado: (2020)

Transglutaminase 2 mediates UV-induced skin inflammation by enhancing inflammatory cytokine production
por: Lee, Seok-Jin, et al.
Publicado: (2017)

S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes
por: Jeong, Eui Man, et al.
Publicado: (2018)

Ethacrynic Acid Inhibits Sphingosylphosphorylcholine-Induced Keratin 8 Phosphorylation and Reorganization via Transglutaminase-2 Inhibition
por: Byun, Hyun Jung, et al.
Publicado: (2013)

Crystal Structure of Transglutaminase 2 with GTP Complex and Amino Acid Sequence Evidence of Evolution of GTP Binding Site
por: Jang, Tae-Ho, et al.
Publicado: (2014)

Overexpression of Plasminogen Activator Inhibitor-1 in Advanced Gastric Cancer with Aggressive Lymph Node Metastasis
por: Suh, Yun-Suhk, et al.
Publicado: (2015)

Transglutaminase 2 regulates osteoclast differentiation via a Blimp1-dependent pathway
por: Kim, Woo-Shin, et al.
Publicado: (2017)

Transglutaminase 2 Prevents Premature Senescence and Promotes Osteoblastic Differentiation of Mesenchymal Stem Cells through NRF2 Activation
por: Lee, Soo-Jin, et al.
Publicado: (2023)

Assessment of the Completeness of Lymph Node Dissection Using Near-infrared Imaging with Indocyanine Green in Laparoscopic Gastrectomy for Gastric Cancer
por: Kim, Tae-Han, et al.
Publicado: (2018)

MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers
por: Choi, Yong Won, et al.
Publicado: (2016)

An integrative approach for exploring the nature of fibroepithelial neoplasms
por: Yun, Jihui, et al.
Publicado: (2022)

Keratinocyte transglutaminase 2 promotes CCR6(+) γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation
por: Shin, Ji-Woong, et al.
Publicado: (2020)

A Rare Case of Intra-Endometrial Leiomyoma of Uterus Simulating Degenerated Submucosal Leiomyoma Accompanied by a Large Sertoli-Leydig Cell Tumor
por: Jeong, Kyungah, et al.
Publicado: (2016)

Transglutaminase-2 Is Involved in Expression of Osteoprotegerin in MG-63 Osteosarcoma Cells
por: Lee, Hye Ja, et al.
Publicado: (2013)

The Value of Postoperative Serum Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 Levels for the Early Detection of Gastric Cancer Recurrence after Curative Resection
por: Lee, Eung-Chang, et al.
Publicado: (2014)

Postoperative morbidity and quality of life between totally laparoscopic total gastrectomy and laparoscopy-assisted total gastrectomy: a propensity-score matched analysis
por: Park, Shin-Hoo, et al.
Publicado: (2021)

A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer
por: Ning, Gang, et al.
Publicado: (2021)

A development of assistant surgical robot system based on surgical-operation-by-wire and hands-on-throttle-and-stick
por: Kim, Myungjoon, et al.
Publicado: (2016)

Modulation of transglutaminase expression in rat skeletal muscle by induction of atrophy and endurance training.
por: Park, S. C., et al.
Publicado: (1994)

Transglutaminase 2 Expression and Its Prognostic Significance in Clear Cell Renal Cell Carcinoma
por: Park, Min Jee, et al.
Publicado: (2015)

Flux variability scanning based on enforced objective flux for identifying gene amplification targets
por: Park, Jong Myoung, et al.
Publicado: (2012)

Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice
por: Oh, Keunhee, et al.
Publicado: (2011)

Short-term Outcomes of Pylorus-Preserving Gastrectomy for Early Gastric Cancer: Comparison Between Extracorporeal and Intracorporeal Gastrogastrostomy
por: Alzahrani, Khalid, et al.
Publicado: (2022)

Down-Regulation of Transglutaminase 2 Stimulates Redifferentiation of Dedifferentiated Chondrocytes through Enhancing Glucose Metabolism
por: Ko, Kyoung-Won, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_opgkasdd6srrm0avtek70ufkn2