Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations

Alpha defensins are anti-microbial peptides of the innate immune system. The defensin A1 and A3 genes are located in a repeat array of variable copy number (the DEFA1A3 locus) and encode the human neutrophil peptides 1, 2 and 3. The possibility that copy number variation (CNV) may be associated with...

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Detalles Bibliográficos
Autores principales: Hughes, Timothy, Hansson, Lars, Akkouh, Ibrahim, Hajdarevic, Riad, Bringsli, Jorunn S., Torsvik, Anja, Inderhaug, Elin, Steen, Vidar M., Djurovic, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272440/
https://www.ncbi.nlm.nih.gov/pubmed/32499510
http://dx.doi.org/10.1038/s41598-020-65675-w

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