Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential

The spread of multi-drug resistance and the slow pace at which antibiotics come onto the market are undermining our ability to treat human infections, leading to high mortality rates. Aiming to overcome this global crisis, antimicrobial peptides are considered promising alternatives to counter bacte...

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Detalles Bibliográficos
Autores principales: Oliveira, Nelson G. J., Cardoso, Marlon H., Velikova, Nadya, Giesbers, Marcel, Wells, Jerry M., Rezende, Taia M. B., de Vries, Renko, Franco, Octávio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272458/
https://www.ncbi.nlm.nih.gov/pubmed/32499582
http://dx.doi.org/10.1038/s41598-020-66164-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272458/
https://www.ncbi.nlm.nih.gov/pubmed/32499582
http://dx.doi.org/10.1038/s41598-020-66164-w

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