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Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome

This study is to test feasibility, safety and the outcome of sagittal en bloc resection of paravertebral primary tumors in the thoracic and the lumbar spine. Sagittal en bloc resection was planned based on WBB classification and performed via combined anterior-posterior or anterior-posterior-lateral...

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Autores principales: Dang, Lei, Liu, Zhongjun, Liu, Xiaoguang, Jiang, Liang, Yu, Miao, Wu, Fengliang, Wei, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272461/
https://www.ncbi.nlm.nih.gov/pubmed/32499491
http://dx.doi.org/10.1038/s41598-020-65326-0
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author Dang, Lei
Liu, Zhongjun
Liu, Xiaoguang
Jiang, Liang
Yu, Miao
Wu, Fengliang
Wei, Feng
author_facet Dang, Lei
Liu, Zhongjun
Liu, Xiaoguang
Jiang, Liang
Yu, Miao
Wu, Fengliang
Wei, Feng
author_sort Dang, Lei
collection PubMed
description This study is to test feasibility, safety and the outcome of sagittal en bloc resection of paravertebral primary tumors in the thoracic and the lumbar spine. Sagittal en bloc resection was planned based on WBB classification and performed via combined anterior-posterior or anterior-posterior-lateral approach in 9 consecutive patients with aggressive benign or malignant paravertebral primary tumors in the thoracic and lumbar spine. Surgical margins were evaluated both radiologically and histopathologically. Follow-up data regarding survival rate, local control, morbidity, hardware failure and postoperative function were collected at around 2 years after surgery. En bloc resection was achieved in all patient with wide margin in 7/9 patients, marginal and intralesional margin in 2/9 patients. Survival rate and local control rate were 100%. There were 4/9 cases of major complications and 2/9 cases of minor complications with an overall morbidity rate of 67% (6/9). All but one patient with intraoperative spinal cord injury were free of neurological deficits and fully mobile in absence of any indication of hardware failure. With a careful choice of surgical procedure, sagittal en bloc resection of paravertebral primary tumor in the thoracic and lumbar spine is feasible, safe and effective.
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spelling pubmed-72724612020-06-05 Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome Dang, Lei Liu, Zhongjun Liu, Xiaoguang Jiang, Liang Yu, Miao Wu, Fengliang Wei, Feng Sci Rep Article This study is to test feasibility, safety and the outcome of sagittal en bloc resection of paravertebral primary tumors in the thoracic and the lumbar spine. Sagittal en bloc resection was planned based on WBB classification and performed via combined anterior-posterior or anterior-posterior-lateral approach in 9 consecutive patients with aggressive benign or malignant paravertebral primary tumors in the thoracic and lumbar spine. Surgical margins were evaluated both radiologically and histopathologically. Follow-up data regarding survival rate, local control, morbidity, hardware failure and postoperative function were collected at around 2 years after surgery. En bloc resection was achieved in all patient with wide margin in 7/9 patients, marginal and intralesional margin in 2/9 patients. Survival rate and local control rate were 100%. There were 4/9 cases of major complications and 2/9 cases of minor complications with an overall morbidity rate of 67% (6/9). All but one patient with intraoperative spinal cord injury were free of neurological deficits and fully mobile in absence of any indication of hardware failure. With a careful choice of surgical procedure, sagittal en bloc resection of paravertebral primary tumor in the thoracic and lumbar spine is feasible, safe and effective. Nature Publishing Group UK 2020-06-04 /pmc/articles/PMC7272461/ /pubmed/32499491 http://dx.doi.org/10.1038/s41598-020-65326-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Dang, Lei
Liu, Zhongjun
Liu, Xiaoguang
Jiang, Liang
Yu, Miao
Wu, Fengliang
Wei, Feng
Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
title Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
title_full Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
title_fullStr Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
title_full_unstemmed Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
title_short Sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
title_sort sagittal en bloc resection of primary tumors in the thoracic and lumbar spine: feasibility, safety and outcome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272461/
https://www.ncbi.nlm.nih.gov/pubmed/32499491
http://dx.doi.org/10.1038/s41598-020-65326-0
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