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Impact of pemetrexed chemotherapy on the gut microbiota and intestinal inflammation of patient-lung-derived tumor xenograft (PDX) mouse models

Chemotherapy remains the gold standard for advanced cancer. Pemetrexed, a chemotherapeutic agent used in non-small cell lung cancer, can induce significant side effects in patients. Although microbiota’s role in the efficacy and/or toxicity of chemotherapy agents has been demonstrated, the impacts o...

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Detalles Bibliográficos
Autores principales: Pensec, Cindy, Gillaizeau, Florence, Guenot, Dominique, Bessard, Anne, Carton, Thomas, Leuillet, Sébastien, Campone, Mario, Neunlist, Michel, Blottière, Hervé M., Le Vacon, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272463/
https://www.ncbi.nlm.nih.gov/pubmed/32499509
http://dx.doi.org/10.1038/s41598-020-65792-6