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Enhancement of gene expression noise from transcription factor binding to genomic decoy sites
The genome contains several high-affinity non-functional binding sites for transcription factors (TFs) creating a hidden and unexplored layer of gene regulation. We investigate the role of such “decoy sites” in controlling noise (random fluctuations) in the level of a TF that is synthesized in stoch...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272470/ https://www.ncbi.nlm.nih.gov/pubmed/32499583 http://dx.doi.org/10.1038/s41598-020-65750-2 |