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Exosomal miRNA-320a Is Released from hAMSCs and Regulates SIRT4 to Prevent Reactive Oxygen Species Generation in POI

Human amniotic mesenchymal stem cells (hAMSCs) were previously shown to effectively rescue ovarian function in a premature ovarian insufficiency (POI) mouse model. The therapeutic mechanism of hAMSC-derived exosomes (hAMSC-Exos) is not fully understood. In this study, the therapeutic mechanism invol...

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Detalles Bibliográficos
Autores principales:	Ding, Chenyue, Qian, Chunfeng, Hou, Shunyu, Lu, Jiafeng, Zou, Qinyan, Li, Hong, Huang, Boxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272510/ https://www.ncbi.nlm.nih.gov/pubmed/32506013 http://dx.doi.org/10.1016/j.omtn.2020.05.013

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