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Base Excision Repair in the Immune System: Small DNA Lesions With Big Consequences

The integrity of the genome is under constant threat of environmental and endogenous agents that cause DNA damage. Endogenous damage is particularly pervasive, occurring at an estimated rate of 10,000–30,000 per cell/per day, and mostly involves chemical DNA base lesions caused by oxidation, depurin...

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Detalles Bibliográficos
Autores principales:	Stratigopoulou, Maria, van Dam, Tijmen P., Guikema, Jeroen E. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272602/ https://www.ncbi.nlm.nih.gov/pubmed/32547565 http://dx.doi.org/10.3389/fimmu.2020.01084

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